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The PepT1 transporter adds another dimension: KPV's anti-inflammatory mechanism is delivered directly into inflamed gut cells via a transporter that is selectively upregulated in diseased tissue

Belimumab has demonstrated a favorable safety profile with minimal risk of adverse effects, even with prolonged use up to 13 years, making it a suitable alternative to traditional immunosuppressive therapies (127)

Efinopepgutida: en un ensayo fase 2 de 145 participantes con IMC inicial de 34,3kg/m2 (33,1% con DM2) efinopepgutida 10mg respecto a semaglutida 1mg mostr una mayor reduccin del contenido de grasa heptica evaluada por resonancia en 24 semanas (72,7% frente a 42,3%, respectivamente) con una prdida de peso similar (8,5% frente a 7,1%, respectivamente)29

Under the fed condition, five participants (18.5%) reported nausea, and two participants each (7.4%) reported vomiting and diarrhea

(PubMed) Carr AC, Lunt H, Wareham NJ, Myint PK